| AVG* SLG* OPS* OBP* Games At-Bats Hits Total Bases Doubles Triples Home Runs RBIs Stolen Bases Caught Stealing Walks Strikeouts |
| Boston Strikeouts - Single Season Leaders |
| Rank | Player | Year | Value |
| 1 | Rudy York | 2017 | 110 |
| 2 | Barney McCosky | 2016 | 57 |
| 3 | Frank Thomas | 2017 | 54 |
| Mel Ott | 2017 | 54 | |
| 4 | Jim Landis | 2017 | 51 |
| 5 | Frankie Frisch | 2016 | 50 |
| 6 | Frank Thomas | 2016 | 49 |
| 7 | Red Rolfe | 2017 | 45 |
| 8 | Charlie Gehringer | 2016 | 44 |
| 9 | Bill Dickey | 2016 | 40 |
| Lefty O'Doul | 2016 | 40 | |
| Mel Ott | 2016 | 40 | |
| 10 | Arky Vaughan | 2016 | 38 |
| Ross Barnes | 2016 | 38 | |
| 11 | Rip Radcliff | 2017 | 37 |
| 12 | Arky Vaughan | 2017 | 30 |
| 13 | Bill Dickey | 2017 | 28 |
| 14 | Minnie Minoso | 2016 | 25 |
| Frankie Frisch | 2017 | 25 | |
| 15 | Charlie Gehringer | 2017 | 24 |
| Lefty O'Doul | 2017 | 24 | |
| 16 | Lou Berberet | 2017 | 22 |
| Ross Barnes | 2017 | 22 | |
| 17 | Wally Moses | 2017 | 16 |
| 18 | Rudy York | 2016 | 14 |
| 19 | Buddy Myer | 2016 | 11 |
| 20 | Luke Appling | 2016 | 9 |
| Lou Criger | 2016 | 9 | |
| 21 | Joe Judge | 2017 | 7 |
| Rip Radcliff | 2016 | 7 | |
| 22 | Red Rolfe | 2016 | 6 |
| 23 | Luke Appling | 2017 | 4 |